The Leyden 2002 clinical evaluation in the Journal of Cosmetic Dermatology compared a copper tripeptide cream and serum against placebo in 67 women with photodamaged skin and found significant improvements in wrinkle depth, skin laxity, clarity, and density at 12 weeks [30]
Can glutathione supplementation support overall health
Rizzo A, Santoni M, Mollica V, Logullo F, Rosellini M, Marchetti A, et al
Discontinue if: Significant adverse reactions occur, you achieve body composition goals, no response after 8-12 weeks at optimal dosing, medical contraindications develop, or pregnancy occurs
Another study found a higher prevalence of C677T polymorphism in BD patients than healthy subjects, while patients with BD with early onset carried one copy of the T allele 62