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Recently, both the receptors have shown to heteromerize in vitro , eliciting synergistic signaling and -arrestin-2 recruitment (300)
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PMID: 38960516, DOI: 10.1016/j.jacc.2024.05.035
And unlike other GLP-1s, it works on just one chemical pathway, which can be harder on the body and may increase side effects like nausea and GI distress, says Dr
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