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The selective metabotropic glutamate receptor 5 antagonist mavoglurant (AFQ056) reduces the incidence of reflux episodes in dogs and patients with moderate to severe gastroesophageal reflux disease

SRB populations decrease as beneficial bacteria better adapted to the slowed transit conditions take hold

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If you want to stay off food noise long-term, you need either: A maintenance protocol (staying on low-dose GLP-1 or stacking alternatives) Addressing the underlying drivers (sleep, meal timing, food environment, stress) Accepting that complete discontinuation requires a period of readjustment The good news: the brain adapts

GI side effects, anesthesia risk with GLP-1 agonists: what to know