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Hyperhomocysteinemia, when detected under basal conditions, was found to be related to recurrent (den Heijer et al, 1995) and/or premature (Falcon et al, 1994) venous thrombosis in subjects less than 40 years old

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Schizophrenia is a complex disorder with positive, negative, and cognitive symptoms, and selective inhibition of either PDE1B or PDE10A may effectively target only one of these domains, making comprehensive treatment difficult and contributing to treatment failure