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Pancreatitis and gallbladder issues: Severe abdominal pain that radiates to the back, nausea, fever, or vomiting while using GLP-1s may indicate inflammation of the pancreas, while upper right abdominal pain, jaundice, fever, and nausea can be due to gallbladder issues such as gallstones

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However, there are a few considerations to keep in mind

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However, elevated MMA and homocysteine concentrations may persist in patients with cobalamin concentrations between 200 and 350 pg/mL