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While evidence remains limited, some studies have suggested a role in regulating microglial activity, reducing neuroinflammation, modulating neurotransmitter levels (e.g., serotonin), and influencing neuronal signaling

The intake does not include a dedicated eating-disorder screen , a substance-use or alcohol screen, a validated PHQ-2 or PHQ-9 depression instrument (the suicidal-ideation question is present but bundled into the GI conditions list rather than getting its own safety context), an allergy screen, a current medications review, a diet or exercise history , a blood pressure reading , or an explicit pregnancy check

Consistent with prior reports on caloric restriction, bariatric surgery, and severe weight loss in humans [16,22,26,28], inflammatory resolution appears to lag behind metabolic recovery

Placement and timing remain consistent for clean readouts

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