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Studies have shown that patients with inflammatory bowel disease (IBD) exhibit specific DNA methylation abnormalities in intestinal tissues, which are linked to disease progression and gut-brain axis dysfunction (Xu et al., 2023)
This is an irreversible process of cell demise, whether through programmed apoptosis or necrosis caused by physical or chemical injury, which can lead to a significant decline or complete loss of retinal function
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Acta 1328 , 261272 (1997)