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Hypertension is the most common preventable risk factor for CVDs (including coronary heart disease, heart failure, stroke, myocardial infarction, atrial fibrillation, and peripheral artery disease), chronic kidney disease, and cognitive impairment, and also the main single factor for deaths and disability worldwide (133)

This discovery has led to a whole new category of treatment called hormone therapy

In more recent times, lorcaserin (Belviq) was also withdrawn, due to an increased risk (albeit only 9%) of cancer [49] , which the FDA deemed as not being outweighed by the benefits of lorcaserin for any identifiable patient population

Despite this beneficial effect, the exact mechanism behind how GLP-1s improve kidney function in individuals with diabetes is not fully understood at this time

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