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key concerns include glycaemic instability, elevated heart rate, fluid retention, and contraindication in active malignancy due to GH stimulation

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Hypertension, ischemic heart disease, patients with atherosclerosis and coronary artery disease, diabetes, chronic lung diseases, smoking and obesity are associated with low baseline GSH levels and reduced GSH/oxidized glutathione (GSSG) ratios (Khanfar and Al Qaroot, 2020

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