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or peripheral vascular disease (secondary prevention) the following course of action is recommended: Offer metformin plus an SGLT2 inhibitor with proven CV benefit (empagliflozin, canagliflozin, dapagliflozin) as initial dual therapy

In other rats, saline (C group, n 6) or WPC (2 g/kg, oral gavage C + WPC group, n 8) was administered for 10 d, following a single dose of saline injection

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