"If any of the Chinese manufacturers launch an oral drug at Rs500 to Rs800 per month, it doesn't just undercut local brands
Dosing approaches used in clinical practice vary considerably and are largely empirical, based on limited evidence rather than controlled clinical trials
It inhibits key molecules that play a role in inflammation, including TNF-, IL-1, and IL-6, mainly through the inhibition of the NF-kB pathway, which is a critical regulator of the immune response and inflammation
AP39 also exhibited antioxidant effects by reducing ROS and MDA levels, increasing GSH levels, and superoxide dismutase (SOD) activity
Sepsis often leads to neurological complications such as delirium and sepsis-associated encephalopathy (SAE), which are linked to increased mortality, prolonged intensive care unit stays, and persistent cognitive impairments (49)