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These decks need to have an abundance of card advantage and mana to keep up with the table, so be generous with your card draw and ramp spells when youre building a deck around one of these cards

Exquisite Blood Part of the famous Blood Bond combo with Sanguine Bond, its an easy and inexpensive kill of the table

Doubling all of the counters you make and cutting in half all of the counters your opponents make

No matter which route you take, the goal stays the same: build the board, make your spells cheap, and overwhelm the table before they can find a clean answer

In fact, Id argue that the only reason poison is even a viable strategy in Commander is because of the existence of proliferate as a mechanic